US Patent Issued to NuCana on July 15 for "Formulations of phosphoramidate derivatives of nucleoside drugs" (British Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,652, issued on July 15, was assigned to NuCana plc (Edinburgh, Great Britain).

"Formulations of phosphoramidate derivatives of nucleoside drugs" was invented by Gordon Kennovin (Central Scotland, Great Britain) and Hugh Griffith (Central Scotland, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to pharmaceutical formulations and formulation strategies of protides (phosphoramidate derivatives of nucleosides) and, in particular, protides useful in the treatment of cancer such as NUC-3373 (5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl (benzoxy-L-alaninyl)] phosphate) and NUC-7738 (3'-deoxyadenosine-5'-O-[phenyl(benzyloxy...