US Patent Issued to Novartis on Oct. 14 for "Substituted 2,4-dioxotetrahydropyrimidines as intermediates in the synthesis of bruton's tyrosine kinase inhibitors" (Swiss, French, German Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,733, issued on Oct. 14, was assigned to Novartis AG (Basel, Switzerland).

"Substituted 2,4-dioxotetrahydropyrimidines as intermediates in the synthesis of bruton's tyrosine kinase inhibitors" was invented by Luca Arista (Riehen, Switzerland), Christina Hebach (Muenchenstein, Switzerland), Gregory John Hollingworth (Basel, Switzerland), Philipp Holzer (Sissach, Switzerland), Patricia Imbach-Weese (Bielefeld, Germany), Julien Lorber (Colmar, France), Rainer Machauer (Ehrenkirchen, Germany), Niko Schmiedeberg (Riehen, Switzerland), Anna Vulpetti (Basel, Switzerland) and Thomas Zoller (Andolsheim, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "Th...