US Patent Issued to Novartis on Oct. 14 for "Manufacture of compounds and compositions for inhibiting the activity of SHP2" (Chinese Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,737, issued on Oct. 14, was assigned to Novartis AG (Basel, Switzerland).

"Manufacture of compounds and compositions for inhibiting the activity of SHP2" was invented by Zhongbo Fei (Shanghai), Huanqing Jia (Changshu, China), Wei Li (Shanghai), Jianhua Wang (Changshu, China) and Huangchao Yu (Suzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following ...