US Patent Issued to Northwestern University on Sept. 16 for "Bifunctional compounds comprising Apcin-A and their use in the treatment of cancer" (Illinois Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,414,995, issued on Sept. 16, was assigned to Northwestern University (Evanston, Ill.).

"Bifunctional compounds comprising Apcin-A and their use in the treatment of cancer" was invented by Yong Wan (Evanston, Ill.), Zhuan Zhou (Evanston, Ill.), Junlong Chi (Evanston, Ill.) and Gary Schiltz (Evanston, Ill.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are compounds of Formula I, or their pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of using such compounds or compositions in inducing Cdc20 degradation in a cell, blocking mitotic progression, inhibiting tumor proliferation, treating cancer, and/...