ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,995, issued on Sept. 16, was assigned to Northwestern University (Evanston, Ill.).
"Bacterial toxins and uses thereof as Ras specific proteases for treating cell proliferation diseases and disorders" was invented by Karla J. F. Satchell (Evanston, Ill.), Irena Antic (Chicago) and Marco Biancucci (Chicago).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are bacterial toxins and uses thereof as specific proteases for Ras sarcoma oncoproteins (Ras proteins). The bacterial toxins may be modified for use as pharmaceutical agents for treating Ras-dependent diseases and disorders including cell proliferation diseases and disorders such as cancer."...