US Patent Issued to NERVIANO MEDICAL SCIENCES on Jan. 13 for "Gem-disubstituted heterocyclic compounds and their use as IDH inhibitors" (Italian Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,395, issued on Jan. 13, was assigned to NERVIANO MEDICAL SCIENCES S.R.L. (Nerviano, Italy).

"Gem-disubstituted heterocyclic compounds and their use as IDH inhibitors" was invented by Francesco Casuscelli (Dairago Milan, Italy), Teresa Disingrini (Vanzago Milan, Italy), Paola Magnaghi (Nerviano Milan, Italy), Stefano Nuvoloni (Milan) and Paolo Orsini (Legnano, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to certain gem-disubstituted heterocyclic compounds, which modulate the activity of Isocitrate Dehydrogenase (IDH). The compounds of this invention are therefore useful in treating diseases caused by mutated IDH1...