ALEXANDRIA, Va., June 18 -- United States Patent no. 12,324,829, issued on June 10, was assigned to NATIONWIDE CHILDREN'S HOSPITAL INC. (Columbus, Ohio).

"Methods for delivery of polynucleotides by adeno-associated virus for lysosomal storage disorders" was invented by Douglas M. McCarty (Pataskala, Ohio) and Haiyan Fu (Pataskala, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods and materials useful for systemically delivering polynucleotides across the blood brain barrier using adeno-associated virus as a vector. For example, the present invention relates to methods and materials useful for systemically delivering Alpha-N-acetylglucosamidinase polynucleotides to t...