US Patent Issued to National University of Singapore on Oct. 14 for "Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells" (Singaporean Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,787, issued on Oct. 14, was assigned to National University of Singapore (Singapore).

"Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells" was invented by Hong Ji Adrian Tan (Singapore) and Dario Campana (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Transgenic T cells and vectors for making transgenic T cells are described. The vectors can include a nucleic acid encoding a membrane-bound anti-IL6 (mb-alL6) single chain variable fragment (scFv), and the transgenic T cells can express mb-alL6. The transgenic T cells are useful for suppressing proliferation of IL-6-dependent c...