ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,527, issued on Aug. 5, was assigned to National University of Singapore (Singapore) and BioLamina AB (Sundyberg, Sweden).
"Differentiation of pluripotent stem cells using laminins LN-511, LN-521 and LN-221" was invented by Karl Tryggvason (Singapore), Yan Wen Yap (Singapore), Sun Yi (Sundyberg, Sweden) and Kristian Tryggvason (Sundyberg, Sweden).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure describes methods of differentiating cardiomyocyte progenitor cells and mature cardiomyocyte cells from pluripotent stem cells. The methods may include differentiating pluripotent stems cells on a substrate including (i) laminin-511 or 521 a...