ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,984, issued on Nov. 4, was assigned to NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (Hyogo, Japan).
"Cancer gene therapy drug" was invented by Toshiro Shirakawa (Hyogo, Japan), Naoto Kunimura (Hyogo, Japan) and Koichi Kitagawa (Hyogo, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a novel cancer gene therapeutic means. More specifically, provided is a nucleic acid having a structure in which (A) a nucleic acid encoding a protein having a CD44 extracellular function, (B) a nucleic acid encoding a protein having a Notch core region function, and (C) a nucleic acid encoding a protein having an HIF-3Alpha4 function are linked in the ...