US Patent Issued to National Research Council of Canada on July 1 for "Blood-brain barrier transmigrating therapeutic compounds and uses thereof" (Canadian Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,671, issued on July 1, was assigned to National Research Council of Canada (Ottawa).

"Blood-brain barrier transmigrating therapeutic compounds and uses thereof" was invented by Hung Fang (Ottawa), Danica Stanimirovic (Ottawa), Arsalan Haqqani (Kanata, Canada), Will Costain (Ottawa) and Gregory Hussack (Ottawa).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a compound comprising an antibody or a fragment thereof operable to transmigrate across the blood-brain barrier (BBB), and a polypeptide related to the treatment of lysosomal storage disease (LSD), for the treatment of Alpha-synucleinopathies, or both. The present in...