US Patent Issued to MyoKardia on July 1 for "Substituted 5,6,7,8-tetrahydropyrido[2,3-dpyrimidine-2,4-diones for treating cardiac diseases" (American, French Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,607, issued on July 1, was assigned to MyoKardia Inc. (Brisbane, Calif.).

"Substituted 5,6,7,8-tetrahydropyrido[2,3-dpyrimidine-2,4-diones for treating cardiac diseases" was invented by Mark Grillo (South San Francisco, Calif.), Brian Kane (San Mateo, Calif.), Johan Oslob (Sunnyvale, Calif.), Min Zhong (Palo Alto, Calif.) and Fabienne Thompson (Paris).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides novel tetrahydropyran (THP)-substituted bicyclic pyrimidinedione compounds, including (6S,7S)-6-fluoro-7-(2-fluoro-5-methylphenyl)-3-(tetrahydro-2H-pyran-4-yl)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (shown ...