US Patent Issued to MILTENYI BIOTEC on April 15 for "In vitro method of reprogramming fibroblast cells into induced pluripotent stem cells by transcription factors mRNAs co-transfected with SOCS1 mRNA wherein the mRNAs have a poly-A tail of at least 2000 adenines" (German Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,950, issued on April 15, was assigned to MILTENYI BIOTEC B.V. & Co. KG (Bergisch Gladbach, Germany).

"In vitro method of reprogramming fibroblast cells into induced pluripotent stem cells by transcription factors mRNAs co-transfected with SOCS1 mRNA wherein the mRNAs have a poly-A tail of at least 2000 adenines" was invented by Marion Jurk (Pulheim, Germany), Stefan Wild (Cologne, Germany) and Andreas Bosio (Cologne, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides the use of a nucleic acid encoding SOCS1 for enhancing the efficacy of introducing at least one nucleic acid of interest into a cell; a method of repea...