ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,663, issued on Nov. 25, was assigned to Merz Pharma GmbH & Co. KGaA (Frankfurt am Main, Germany).

"Use of botulinum neurotoxin in the treatment of sialorrhea" was invented by Janos Csikos (Frankfurt am Main, Germany), Irena Pulte (Frankfurt am Main, Germany), Michael Althaus (Osten, Germany), Markus Kruer (Kelkheim, Germany) and Nico Wegener (Frankfurt am Main, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to improved uses of botulinum neurotoxins in the treatment of sialorrhea or diseases or conditions relating to increased saliva production. In particular are botulinum neurotoxins disclosed which are administered in...