US Patent Issued to Merck Sharp & Dohme on April 22 for "Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes" (New Jersey, Pennsylvania Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,109, issued on April 22, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes" was invented by Jian Liu (Edison, N.J.), Younong Yu (East Brunswick, N.J.), Joseph A. Kozlowski (Princeton, N.J.), Deyou Sha (Yardley, Pa.), Wensheng Yu (Edison, N.J.), Joseph M. Kelly (Parlin, N.J.) and Scott E. Wolkenberg (Wyndmoor, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to Compounds of Formula I: and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, R3, A and B are as defined herei...