ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,458, issued on June 24, was assigned to Memorial Sloan Kettering Cancer Center (New York).
"Use of the IL-15/IL-15RAlpha complex in the generation of antigen-specific T cells for adoptive immunotherapy" was invented by Richard John O'Reilly (Roxbury, Conn.), Bo Dupont (Harrison, N.Y.), Aisha Nasreen Hasan (Blue Bell, Pa.), Annamalai Selvakumar (West Orange, N.J.) and Xiao-Rong Liu (Astoria, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods of generating antigen-specific T cells for therapeutic administration to a human patient having or suspected of having a pathogen or cancer, utilizing soluble IL-15/IL-15RAlpha comple...