US Patent Issued to Memorial Sloan-Kettering Cancer Center on Feb. 10 for "IL-36 secreting immunoresponsive cells and uses thereof" (New York Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,440, issued on Feb. 10, was assigned to Memorial Sloan-Kettering Cancer Center (New York).

"IL-36 secreting immunoresponsive cells and uses thereof" was invented by Anthony Daniyan (New York) and Renier J. Brentjens (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to an immunoresponsive cell comprising an antigen-recognizing receptor (e.g., a chimeric antigen receptor (CAR) or a T cell receptor (TCR)), and expressing increased level of IL-36. In certain embodiments, the engineered immunoresponsive cells are anti...