US Patent Issued to MeiraGTX UK II on July 15 for "Regulation of gene expression via aptamer-mediated control of self-cleaving ribozymes" (New York, New Jersey, Massachusetts Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,199, issued on July 15, was assigned to MeiraGTX UK II Ltd. (London).

"Regulation of gene expression via aptamer-mediated control of self-cleaving ribozymes" was invented by Michael J. Volles (Cambridge, Mass.), Olivier F. Danos (New York), Alex R. Boyne (Jersey City, N.J.), Veronique Zennou (Jersey City, N.J.) and Xuecui Guo (Oyster Bay, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides polynucleotide constructs for the regulation of gene expression by aptamer-based modulation of self-cleaving ribozymes and methods of using the constructs to regulate gene expression in response to the presence or absence of a ligand that bi...