ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,093, issued on Nov. 25, was assigned to Medizinische Hochschule Hannover (Hannover, Germany).

"Production of megakaryocytes in bioreactors" was invented by Rainer Blasczyk (Isernhagen, Germany) and Constanca Ferreira De Figueiredo (Neustadt am Rubenberge, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "An in vitro process for producing megakaryocytes, and optionally platelets from the megakaryocytes, including the steps of cultivating stem cells, e.g. induced pluripotent stem cells, to generate aggregated pluripotent stem cells, preferably cultivating the aggregates in suspension in medium, inducing differentiation in these aggregates, and is...