ALEXANDRIA, Va., Jan. 29 -- United States Patent no. 12,209,078, issued on Jan. 28, was assigned to MBQ Pharma (Canovanas, Puerto Rico).
"Crystalline forms of carbazole inhibitors of RhoGTPase for the treatment of disease" was invented by Jocelyn M. Jimenez Cruz (San Sebastian, Puerto Rico), Vilmali Lopez-Mejias (San Juan, Puerto Rico) and Torsten Stelzer (San Juan, Puerto Rico).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are crystalline forms of compounds for the inhibition of RhoGTPase. Also disclosed herein are compounds, pharmaceutical compositions, and methods of treatment of RhoGTPase-mediated diseases, such as hyperproliferative and neoplastic diseases."
The patent was filed on Oct...