US Patent Issued to Max-Planck-Gesellschaft zur Forderung der Wissenschaften on Oct. 28 for "Peptides as inhibitors of fibrotic matrix accumulation" (German Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,551, issued on Oct. 28, was assigned to Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V. (Munich).

"Peptides as inhibitors of fibrotic matrix accumulation" was invented by Inaam Nakchbandi (Hirschberg, Germany), Stefan Hamelmann (Heidelberg, Germany) and Stephan Uebel (Wofratshausen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "Peptides that inhibit overproduction and/or excess accumulation of extracellular matrix in an organ or tissue are described. The inventive peptides have the general sequence Xa-Leu-Gln-Gly-Xb (SEQ ID NO: 1), wherein Xa is selected from Pro-Gly, Gly and Ac-Gly and Xb is selected from Glu and Glu-NH2, and...