US Patent Issued to Massachusetts Institute of Technology on Nov. 25 for "Brush prodrugs and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,683, issued on Nov. 25, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Brush prodrugs and uses thereof" was invented by Jeremiah A. Johnson (Boston), Yivan Jiang (Revere, Mass.) and Hung Vanthanh Nguyen (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides, in some aspects, macromonomers of Formula (I), and salts thereof; methods of preparing the macromonomers, and salts thereof; Brush prodrugs (polymers); methods of preparing the Brush prodrugs; compounds of Formula (II); conjugates of Formula (III), and salts thereof; pharmaceutical compositions comprising a Brush prodrug, or a...