ALEXANDRIA, Va., June 12 -- United States Patent no. 12,295,986, issued on May 13, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Combination immunotherapy for treatment of melanoma, colon or non-small cell lung cancers" was invented by Chensu Wang (Allston, Mass.), Karl Dane Wittrup (Boston) and Darrell J. Irvine (Arlington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a method of treating cancer with a priming dose of combination immunotherapy comprising IL-2 (e.g., extended-PK IL-2), an immune checkpoint inhibitor, a tumor targeting antibody or integrin-binding polypeptide, and optional cancer vaccine, administered prior to maintenance do...