ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,497, issued on Oct. 14, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.) and The General Hospital Corp. (Boston).
"Compositions and methods for enhancing Wnt signaling for treating cancer" was invented by George Eng (Cambridge, Mass.), Omer Yilmaz (Cambridge, Mass.) and Jonathan Braverman (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions for enhancing Wnt signaling pathway activities in a tissue of a subject have been developed for the treatment of cancer, in particular cancers with one or more mutations in the APC (adenomatous polyposis coli) gene. Preferably, the amount of the composi...