US Patent Issued to Massachusetts Institute of Technology, Children's Medical Center, Whitehead Institute for Biomedical Research on Oct. 28 for "Nanobody based imaging and targeting of ECM in disease and development" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,576, issued on Oct. 28, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.), Children's Medical Center Corp. (Boston) and Whitehead Institute for Biomedical Research (Cambridge, Mass.).

"Nanobody based imaging and targeting of ECM in disease and development" was invented by Richard O. Hynes (Winchester, Mass.), Noor Jailkhani (Cambridge, Mass.), Hidde L. Ploegh (Boston) and Yushu J. Xie (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for developing disease-related nanobodies and related products and kits are provided. The disease-specific proteins are extracellular matrix (ECM) proteins, domains or epito...