ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,728, issued on Feb. 10, was assigned to LONZA SALES AG (Basel, Switzerland).
"Treatment of cancer metastasis by targeting exosome proteins" was invented by Kevin P. Dooley (Boston) and Douglas E. Williams (Boston).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a therapeutic method of treating cancer metastasis by inducing clearance of EVs using a binding agent specific to an EV protein. The method utilizes one or more binding agents specific to EV proteins, where the EV proteins are selected from prostaglandin F2 receptor negative regulator (PTGFRN); basigin (BSG); immunoglobulin superfamily member 2 (IGSF2); immunoglo...