ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,079, issued on April 22, was assigned to Lead Discovery Center GmbH (Dortmund, Germany).

"Quinoline derivatives, processes for their preparation and uses thereof for the treatment of cancer" was invented by Raffaella Di Lucrezia (Wuppertal, Germany), Tim Bergbrede (Dortmund, Germany), Peter Nussbaumer (Dortmund, Germany) and Peter Schroder (Dortmund, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of the general formula (I): (I), wherein V, W, M, R, R and Y have the designations cited below, or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof, and to processes for the prepa...