US Patent Issued to KYOTO BIOPHARMACEUTICALS on July 1 for "Enhancement of antibacterial actions of a depsipeptide antibiotic using synergistic amounts of boric acid" (American, Japanese Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,343,374, issued on July 1, was assigned to KYOTO BIOPHARMACEUTICALS INC. (Kyoto, Japan).

"Enhancement of antibacterial actions of a depsipeptide antibiotic using synergistic amounts of boric acid" was invented by Jerome J. Schentag (Buffalo, N.Y.) and Hirofumi Nakajima (Kobe, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "An external or topical formulation for treatment or prevention of infections involving body surfaces using a depsipeptide antibiotic drug such as lotilibcin having improved efficacy and safety is provided. The antibacterial effect of lotilibcin tested in infectious models is substantially enhanced by addition of boric acid in a lo...