ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,643, issued on Nov. 4, was assigned to KAGOSHIMA UNIVERSITY (Kagoshima, Japan) and OSAKA UNIVERSITY (Osaka, Japan).
"Antidepressant/anxiolytic drug in which PAC1 receptor antagonist is used" was invented by Takashi Kurihara (Kagoshima, Japan), Ichiro Takasaki (Toyama, Japan), Hitoshi Hashimoto (Osaka, Japan), Atsuko Hayata (Osaka, Japan) and Yusuke Shintani (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to an antidepressant/anxiolytic drug comprising a compound represented by the following formula (I) or (II),wherein R1 is a hydrogen atom, a C1-6-alkyl group, a C1-6-alkoxy group, a C2-6-alkenyloxy group, a halogen...