ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,337, issued on Dec. 16, was assigned to JOINT BIOSCIENCES (SH) LTD. (Shanghai).

"Oncolytic virus vaccine and drug for treating tumors by combining oncolytic virus vaccine with immune cells" was invented by Guoqing Zhou (Shanghai), He Yang (Shanghai), Fan Zhang (Shanghai) and Suhong Zhang (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application relates to an attenuated oncolytic virus strain, an oncolytic virus vaccine and a drug for treating tumors by combining the oncolytic virus vaccine with immune cells. The present application provides a new attenuated oncolytic virus strain by a site-directed mutation of a matrix protein...