US Patent Issued to JIANGNAN UNIVERSITY on Nov. 25 for "Glutamate decarboxylase mutant with improved pH tolerance and use thereof in synthesis of gamma-aminobutyric acid" (Chinese Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,112, issued on Nov. 25, was assigned to JIANGNAN UNIVERSITY (Jiangsu, China).

"Glutamate decarboxylase mutant with improved pH tolerance and use thereof in synthesis of gamma-aminobutyric acid" was invented by Zhiming Rao (Wuxi, China), Jin Han (Wuxi, China), Taowei Yang (Wuxi, China), Meijuan Xu (Wuxi, China) and Xian Zhang (Wuxi, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a glutamate decarboxylase mutant with improved pH tolerance and use thereof in synthesis of gamma-aminobutyric acid. The mutant is obtained by mutating glutamate decarboxylase having an amino acid sequence as shown in SEQ ID NO. 3. The enzyme acti...