US Patent Issued to Iowa State University Research Foundation on July 1 for "Anaerobic preconditioning of cells for improved in vitro protein production" (Iowa Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,873, issued on July 1, was assigned to Iowa State University Research Foundation Inc. (Ames, Iowa).

"Anaerobic preconditioning of cells for improved in vitro protein production" was invented by Denis Tamiev (Ames, Iowa) and Nigel Forest Reuel (Ames, Iowa).

According to the abstract* released by the U.S. Patent & Trademark Office: "Various aspects relate to a cell-free protein expression method. The method includes exposing a microorganism to substantially anaerobic growth conditions to produce a conditioned microorganism. The method further includes lysing the conditioned microorganism to produce a lysate. The method further includes combining the lysate with a nucleic acid and pr...