ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,226,434, issued on Feb. 18, was assigned to Iovance Biotherapeutics Inc. (San Carlos, Calif.).

"Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy" was invented by Seth Wardell (Tampa, Fla.), James Bender (Rancho Santa Margarita, Calif.) and Michael T. Lotze (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in...