ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,888, issued on Sept. 23, was assigned to INSTITUT DE CARDIOLOGIE DE MONTREAL (Montreal, Canada) and AFFINA BIOTECHNOLOGIES INC. (Valhalla, N.Y.).
"Methods of treating elevated plasma cholesterol" was invented by Alan Berezov (White Plains, N.Y.), Alexander Vinitsky (New York), Steve Poirier (Montreal, Canada) and Gaetan Mayer (Montreal, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of Table 1, which are encompassed by Formula I and/or Formula II, Ill, IV, V, or VI, and pharmaceutically acceptable salts, solvates or compositions thereof. Compounds of Table 1 are PCSK9 interacting small molecules tha...