ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,443, issued on April 29, was assigned to INSILICO MEDICINE IP Ltd. (Hong Kong, Hong Kong).

"Bycyclic JAK inhibitors and uses thereof" was invented by Aleksandrs Zavoronkovs (Pak Shek Kok, Hong Kong), Yan Ivanenkov (Moscow), Aleksandr Aliper (Moscow) and Anton S. Vantskul (Moscow).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds of Formulas (I), (II), (III), and (IV)and subformulas thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), (II), (III), or (IV) and methods of using the compounds, e.g., in the treatment of immune disorders, infl...