US Patent Issued to ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI on Feb. 4 for "Cell-specific expression of modRNA" (New York Inventors)

ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,215,336, issued on Feb. 4, was assigned to ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York).

"Cell-specific expression of modRNA" was invented by Lior Zangi (New York) and Ajit Magadum (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is an expression regulatory system for cell-specific transcription (expression) of a protein of interest, for example a cell cycle inducer that reactivates proliferation in adult or neonatal cardiomyocytes or insulin-producing beta cells. The expression regulatory system comprises a first nucleic acid that encodes a microRNA recognition element that specifically binds a target cell miR, and a translation ...