ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,967, issued on July 15, was assigned to HRYZ (SHANGHAI) BIOTECH Co. (Shanghai) and HRYZ (GUANGZHOU) BIOTECH Co. (Guangzhou, China).

"Methods of obtaining tumor-specific T cell receptors" was invented by Xiangjun Zhou (Shenzhen, China), Yanyan Han (Shenzhen, China) and Xihe Chen (Shenzhen, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided methods of obtaining a plurality of T cell receptors specifically recognizing a target tumor antigen peptide from an individual that has clinically benefitted from an immunotherapy, such as Multiple Antigen Specific Cell Therapy. Also provided tumor-specific TCRs, engineered immune cells expressing the T...