US Patent Issued to Howard Hughes Medical Institute on July 15 for "Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit" (Virginia Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,360,106, issued on July 15, was assigned to Howard Hughes Medical Institute (Chevy Chase, Md.).

"Photochromic xanthene fluorophores and their utility in live-cell imaging beyond the diffraction limit" was invented by Luke Lavis (Leesburg, Va.) and Fadi M. Jradi (Arlington, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is generally directed to novel fluorophores and their use in imaging methods. In one case, the present invention provides a compound according to the structure shown in FIG. 20A. In another case, the present invention provides a method of imaging one or more cellular structures within one or more cells using a co...