ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,767, issued on April 15, was assigned to HOWARD HUGHES MEDICAL INSTITUTE (Chevy Chase, Md.).
"Chemigenetic calcium indicators" was invented by Eric R. Schreiter (Leesburg, Va.), Luke D. Lavis (Ashburn, Va.), Claire Deo (Heidelberg, Germany), Hersh Bhargava (San Francisco) and Ahmed Abdelfattah (Barrington, R.I.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A chemigenetic calcium indicator and a method of measuring calcium are provided. The chemigenetic calcium indicator includes a calcium-binding protein domain attached to a ligand binding protein domain. The method of measuring calcium includes administering a chemigenetic calcium indicator to a su...