ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,862, issued on Sept. 23, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).
"Use of a cathepsin s inhibitor against the formation of anti-drug antibodies" was invented by Christian Klein (Schlieren, Switzerland), Fabrice Alain Andre Kolb (Basel, Switzerland), Marianne Manchester Young (Basel, Switzerland), Syed Sohail Ahmed (Basel, Switzerland) and Juliana Mattos De Almeida Bessa (Basel, Switzerland).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates in particular to a cathepsin S inhibitor for use in a method for reducing or preventing the formation of anti-drug antibodies (ADA) against a therapeutic agent in a s...