US Patent Issued to Hoffmann-La Roche on Sept. 23 for "Spiro (isobenzofuranazetidine) compounds for the treatment of autoimmune disease" (Chinese Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,252, issued on Sept. 23, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Spiro (isobenzofuranazetidine) compounds for the treatment of autoimmune disease" was invented by Jianguo Chen (Shanghai), Weixing Zhang (Shanghai), Zhisen Zhang (Shanghai) and Wei Zhu (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula (I), wherein R1, R3, Y and A are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds."

The patent was filed on Nov. 18, 2020, under Application No....