US Patent Issued to Hoffmann-La Roche on Nov. 4 for "Synthesis of trans-8-chloro-5-methyl-1 -[4-(pyridin-2-yloxy)-cyclohexyl-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[eazulene and crystalline forms thereof" (German, French, Swiss Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,947, issued on Nov. 4, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Synthesis of trans-8-chloro-5-methyl-1 -[4-(pyridin-2-yloxy)-cyclohexyl-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[eazulene and crystalline forms thereof" was invented by Benno Rothenhaeusler (Loerrach, Germany), Rene Trussardi (Birsfelden, Switzerland), Fabienne Hoffmann-Emery (Weil am Rhein, Germany), Urs Schwitter (Reinach, Switzerland), Jean-Michel Adam (Village-Neuf, France), Olaf Grassmann (Loerrach, Germany), Thomas Hartung (Loerrach, Germany), Frederic Ran (Kembs, France), Ralph Diodone (Breisach, Germany), Christophe Pfleger (Mulhouse, France) and Bjorn Bartels (Schopfheim, Germany).

Accordi...