ALEXANDRIA, Va., March 12 -- United States Patent no. 12,247,036, issued on March 11, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Tricyclic compounds for the treatment of cancer" was invented by Jianguo Chen (Shanghai), Lei Guo (Shanghai), Haixia Liu (Shanghai), Hong Shen (Shanghai), Junwei Xi (Shanghai), Weixing Zhang (Shanghai), Dan Zhao (Shanghai) and Wei Zhu (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula (Ib),wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds."

The p...