US Patent Issued to Hoffmann-La Roche on Jan. 28 for "Isoindolinone derivatives as selective allosteric inhibitors of Egfr mutant cancers" (Swiss, French, American, German Inventors)

ALEXANDRIA, Va., Jan. 29 -- United States Patent no. 12,209,091, issued on Jan. 28, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Isoindolinone derivatives as selective allosteric inhibitors of Egfr mutant cancers" was invented by Martin Duplessis (Somerville, Mass.), Annick Goergler (Colmar, France), Georg Jaeschke (Basel, Switzerland), Buelent Kocer (Maulburg, Germany), Bernd Kuhn (Reinach BL, Switzerland), Kiel Lazarski (Boston), Yanke Liang (Belmont, Mass.), Yvonne Alice Nagel (Basel, Switzerland), Ulrike Obst Sander (Reinach BL, Switzerland), Antonio Ricci (Biel-Benken, Switzerland), Daniel Rueher (Raedersdorf, France) and Sandra Steiner (Sursee, Switzerland).

According to the abstract* released by the U.S. Patent & T...