US Patent Issued to Hoffmann-La Roche on April 15 for "Process for the preparation of exo-tert-butyl N-(3-azabicyclo[3.2.1octan-8-yl)carbamate" (Chinese Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,709, issued on April 15, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Process for the preparation of exo-tert-butyl N-(3-azabicyclo[3.2.1octan-8-yl)carbamate" was invented by Weichun Chen (Shanghai) and Guocai Zhang (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a process for the preparation of a compound (I) or pharmaceutically acceptable salt thereof, which is useful as the key intermediate for the synthesis of compounds for prophylaxis and treatment of a disease associated with the deposition of Beta-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cereb...