ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,470, issued on July 29, was assigned to HEALTH RESEARCH INC. (Buffalo, N.Y.).
"Compositions and methods for use of recombinant T cell receptors for direct recognition of tumor antigen" was invented by Kunle Odunsi (Williamsville, N.Y.), Junko Matsuzaki (Williamsville, N.Y.) and Takemasa Tsuji (Williamsville, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compositions and methods for prophylaxis and/or therapy of a variety of cancers which express a NY-ESO-1 antigen. Included are recombinant T cell receptors (TCRs), polynucleotides encoding them, expression vectors that include the polynucleotides, and cells into which the polynucle...