ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,946, issued on April 15, was assigned to Health Research Inc. (Buffalo, N.Y.).

"Compositions and methods for rapid cloning of t-cell receptors" was invented by Kunle Odunsi (Williamsville, N.Y.), Richard Koya (Williamsville, N.Y.) and Takemasa Tsuji (Williamsville, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods, compositions, recombinant DNA molecules, and kits for cloning T cell receptors (TCRs). The methods facilitate construction of TCR expression libraries from biological samples containing antigen-specific T cells, including but not limited to tumor biopsies, including frozen tumor biopsies. Peripheral T cells that were...