ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,323, issued on Dec. 30, was assigned to HANGZHOU XINGAO BIOTECHNOLOGY Co. LTD. (Zhejiang, China).

"Method of treatment of colorectal, breast and lung cancer with metal containing immune agonist complexes" was invented by Xiangshi Tan (Hangzhou, China), Daofeng Xiang (Hangzhou, China) and Jianwu Pei (Hangzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A natural immune agonist complex, consisting of an immune agonist and a targeted liposome, where the immune agonist is M(cGAMP)Ln. The targeted liposome is formed by a nanobody targeting a tumor microenvironment, a cell membrane-targeted penetrating peptide, or a blood-brain barrier-targeted ...