ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,472,265, issued on Nov. 18, was assigned to HANGZHOU DAC BIOTECH Co. LTD. (Hangzhou, China).
"Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers" was invented by Yongxin Robert Zhao (Hangzhou, China), Qingliang Yang (Hangzhou, China), Yuanyuan Huang (Hangzhou, China), Hangbo Ye (Hangzhou, China) and Huihui Guo (Hangzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to linkers having a group of propiolyl, substituted acryl (acryloyl), or disubstituted propanoyl, and using such linkers for the conjugation of compounds, in parti...