ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,642, issued on July 1, was assigned to H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC. (Tampa, Fla.) and THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia).

"Variant survivin vaccine for treatment of myeloma" was invented by Frederick L. Locke (Lutz, Fla.), Dario Altieri (Philadelphia), Scott Antonia (Land O'Lakes, Fla.), Claudio Anasetti (Saint Petersburg, Fla.) and Dmitry Gabrilovich (Villanova, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention concerns a variant (double mutant form) of the survivin polypeptide; nucleic acid molecules encoding the survivin variant; antigen presenting cells (APCs) such as dendritic ce...